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Chronic blockade of GLP-1R with intra 3rd ventricular infusion of exendin (9–39) increases food intake and fat mass [700]
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Clinically, GLP-1RAs could lead to an improvement in cognitive function, which is often found to be impaired across several conditions such as psychosis 240 and mood disorders 241 , eventually leading to an overall benefit as observed in some of the included studies (Tables 4 and 5)
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